- Name: Alexander Karasev, Ph.D.
- Institution: University of Idaho
- Department: Plant, Soil, & Entomological Sciences
- Phone: 208-885-2350
- Email: email@example.com
Summary: My program is focused on studies of plant viruses, with an emphasis on virus-host interactions and virus genes responsible for disease induction and spread. We develop methods for rapid diagnostics of viruses based on PCR, RT-PCR, and various immunological techniques. We are also interested in antigenic structure of viruses which we address through mapping epitopes for virus-specific antibodies. Minimum Classes: N/A, but Chemistry classes taken are very useful in the lab Projects: Two potential projects are proposed:
- Sequencing of several whole genomes of Potato virus Y (PVY) from our North American collection of PVY isolates or collected in the field, with subsequent bioinformatics analysis of the recombinant structure, phylogeny, biological phenotypes, and serological reactivity with select monoclonal antibodies. The overall goal – to correlate biological properties of the PVY strains with specific genetic signatures.
- Characterization of newly found isolates of Bean common mosaic virus (BCMV), originated from the USDA-ARS (Pullman) world-wide bean germplasm collection. Will include biological typing on bean differentials, serological and whole genome sequence analysis. Again, the overall goal – to correlate biological properties of BCMV strains with specific genetic signatures.